PUBLICATIONS

(# Equal contribution, * Corresponding author)
  • Dynamics of Staphylococcus aureus Cas9 in DNA target association and dissociation
    Zhang, S.Q.#, Zhang, Q.#, Hou, X.M., Guo, L.J., Wang, F.Z., Bi, L.L., Zhang, X., Li, H.H., Wen, F.C., Xi, X.G., Huang, X.X., Shen, B., and Sun, B.*EMBO Reports 21, e50184. (2020). (Link)
  • Human RPA activates BLM’s bidirectional DNA unwinding from a nick
    Qin, Z.H.#, Bi, L.L.#, Hou, X.M., Zhang, S.Q., Zhang, X., Lu, Y., Li, M., Modesti, M., Xi, X.G.*, and Sun, B.*eLife 9, e54098. (2020). (Link)
  • The post-PAM interaction of RNA-guided spCas9 with DNA dictates its target binding and dissociation
    Zhang, Q.#, Wen, F.C.#, Zhang, S.Q., Jin, J.C., Bi, L.L., Lu, Y., Li, M., Xi, X.G., Huang, X.X., Shen, B.*, and Sun, B.* Science Advances 5, eaaw9807. (2019). (Link)
  • In vitro biochemical assays using biotin labels to study protein-nucleic acid interactions
    Yu, L.N.#, He, W.X.#, Xie, J.#, Guo, R.#, Ni, J., Zhang, X., Xu, Q.S., Wang, C.F., Yue, Q.L., Li, F.F., Luo. M.C., Sun, B.*, Ye, L.*, and Zheng, K.* Journal of Visualized Experiments 149, e59830. (2019). (Link)
  • MOV10L1 binds RNA G-quadruplex in a structure-specific manner and resolves it more efficiently than MOV10
    Zhang, X.#, Yu, L.N.#, Ye, S.S.#, Xie, J., Huang, X.X., Zheng, K.*, and Sun, B.* iScience 17, 36-48. (2019). (Link)
  • Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
    Gui, X.R., Luo, F., Li, Y.C., Zhou, H., Qin, Z.H., Liu, Z.Y., Gu. J.G., Xie, M.Y., Zhao, K., Dai, B., Shin, W.S., He, J.H., He, L., Jiang. L., Zhao, M.L., Sun, B., Li, X.M., Liu, C.*, and Li, D.* Nature Communications 10, 2006. (2019). (Link)
  • Rescuing replication from barriers: mechanistic insights from single-molecule studies
    Sun, B.* Molecular and Cellular Biology 39, e00576-18. (2019). (Link)
  • Real-time observation of nucleoplasmin-mediated DNA decondensation and condensation reveals its specific functions as a chaperone
    Huo, X.M.#, Meng, L.F.#, Jiang, T., Li, M., Sun, F.Z., Sun, B.*, and Li, J.K.* Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1861, 743-751. (2018). (Link)
  • Helicase promotes replication re-initiating from an RNA transcript
    Sun, B.*, Singh, A., Sultana, S., Inman, J.T., Patel, S.S., and Wang, M.D.* Nature Communications 9, 2306. (2018). (Link)
  • Single-molecule optical-trapping techniques to study molecular mechanisms of a replisome
    Sun, B. and Wang, M.D.*Methods in Enzymology 582, 55-84. (2017). (Link)
  • Single-molecule perspectives on helicase mechanisms and functions
    Sun, B. and Wang, M.D.*Critical Reviews in Biochemistry and Molecular Biology 51, 15-25. (2016). (Link)
  • T7 replisome directly overcomes DNA damage
    Sun, B., Pandey, M., Inman, J.T., Yang, Y., Kashlev, M., Patel, S.S., and Wang, M.D.* Nature Communications 6, 10260. (2015). (Link)
  • ATP-induced helicase slippage reveals highly coordinated subunits
    Sun, B.#, Johnson, D.S.#, Patel, G., Smith, B.Y., Pandey, M., Patel, S.S.*, and Wang, M.D.* Nature 478, 132-135. (2011). (Link)
  • A257T linker region mutant of T7 helicase-primase protein is defective in DNA loading and rescued by T7 DNA polymerase
    Patel, G., Johnson, D.S., Sun, B., Pandey, M., Yu, X., Egelman, E.H., Wang, M.D., and Patel, S.S.* Journal of Biological Chemistry 286, 20490-20499. (2011). (Link)
  • Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding
    Sun, B., Wei, K.J., Zhang, B., Zhang, X.H., Dou, S.X., Li, M.*, and Xi, X.G.* The EMBO Journal 27, 3279-3287. (2008). (Link)
  • An improved single molecule manipulation apparatus and its applications
    Wang, X.L., Zhang, X.H., Wei, K.J., Sun, B., and Li, M.*Acta Physica Sinica 57, 3905-3910. (2008). (Link)
  • Single molecule manipulation and single molecule biophysics
    Ran, S.Y., Sun, B., and Li, M.*Physics 36, 228-235. (2007). (Link)